Vaginitis Research Today is a free monthly online journal that collates and summarizes the latest research about Vaginitis, including details on bacterial vaginitis, candida, symptoms, treatment,.

Genitourinary infections after a routine pelvic exam.

Tiemstra JD, Chico PD, Pela E

Family Medicine Center, University of Illinois at Chicago College of Medicine Chicago.

Published 9 May 2011 in J Am Board Fam Med, 24(3): 296-303.
Full-text of this article is available online (may require subscription).

Articles on Vaginitis published 9 May 2011:

Prevalence and susceptibility of Saccharomyces cerevisiae causing vaginitis in Greek women.   Anaerobe.

Saccharomyces cerevisiae is an ascomycetous yeast, that is traditionally used in wine bread and beer production. Vaginitis caused by S. cerevisiae is rare. The aim of this study was to evaluate the frequency of S. cerevisiae isolation from the vagina in two groups of women and determined the in vitro susceptibility of this fungus. SUBJECTS AND METHODS: Vaginal samples were collected from a total of262 (asymptomaticandsymptomatic) women with vaginitis attending the centre of family planning of ... [Abstract] [Full-text]

Anal Sex, Vaginal Practices, and HIV Incidence in Female Sex Workers in Urban Kenya: Implications for the Development of Intravaginal HIV Prevention Methods.   AIDS Res Hum Retroviruses.

Abstract Multiple intravaginal HIV prevention methods, including microbicide gels, barriers, and intravaginal rings, are in clinical development in Africa. Development of intravaginal HIV prevention products requires an understanding of sexual behavior, sexually transmitted infection (STI), and vaginitis prevalences, and sexual and vaginal practices in potential target populations. We assessed these factors in a cohort of Kenyan female sex workers (FSW). Women who reported exchanging sex for ... [Abstract] [Full-text]

Articles on Vaginitis published 3 May 2011:

Candida albicans, a major human fungal pathogen.   J Microbiol, 49(2): 171-7.

Candida albicans is the most common human fungal pathogen (Beck-Sague and Jarvis, 1993). It is normally a harmless commensal organism. However, it is a opportunistic pathogen for some immunologically weak and immunocompromised people. It is responsible for painful mucosal infections such as the vaginitis in women and oral-pharangeal thrush in AIDS patients. In certain groups of vulnerable patients it causes severe, life-threatening bloodstream infections and it causes severe, life-threatening ... [Abstract] [Full-text]

Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of TH-302, a Hypoxia-Activated Prodrug, in Patients with Advanced Solid Malignancies.   Clin Cancer Res, 17(9): 2997-3004.

[Abstract] [Full-text]

Articles on Vaginitis published 28 April 2011:

Interpreting the epidemiology and natural history of bacterial vaginosis: Are we still confused?   Anaerobe.

Bacterial vaginosis (BV) is a common cause of vaginitis and increases women's risk of pelvic inflammatory disease, adverse pregnancy outcomes, and risk of STD/HIV acquisition. The etiology of BV is unclear, though it is believed to involve loss of vaginal hydrogen peroxide-producing lactobacilli and acquisition of complex bacterial communities that include many fastidious BV-associated bacteria (BVAB) that have recently been detected using PCR methods. Treatment failure (persistence) is common, ... [Abstract] [Full-text]

Articles on Vaginitis published 22 April 2011:

Efficacy of Recombinant Human Mannose Binding Lectin Alone and in Combination with Itraconazole Against Murine Candida albicans vaginitis.   Immunol Invest.

Mannan binding lectin (MBL) deficiency has been associated with increased susceptibility to vaginitis in humans due to Candida albicans. In these studies we assessed the utility of recombinant human MBL (rhMBL) as a therapeutic against experimental C. albicans vaginitis. After intravenous treatment of uninfected mice with 75 μg of rhMBL, rhMBL was detected in the serum and peritoneal lavage fluid; rhMBL was detected in the serum of infected mice 2 and 24 hours post-dose, and at very low ... [Abstract] [Full-text]

Efficacy of Recombinant Human Mannose Binding Lectin Alone and in Combination with Itraconazole Against Murine Candida albicans vaginitis.   Immunol Invest.

Mannan binding lectin (MBL) deficiency has been associated with increased susceptibility to vaginitis in humans due to Candida albicans. In these studies we assessed the utility of recombinant human MBL (rhMBL) as a therapeutic against experimental C. albicans vaginitis. After intravenous treatment of uninfected mice with 75 μg of rhMBL, rhMBL was detected in the serum and peritoneal lavage fluid; rhMBL was detected in the serum of infected mice 2 and 24 hours post-dose, and at very low ... [Abstract] [Full-text]

Articles on Vaginitis published 11 April 2011:

Interobserver reliability of microscopic assessment of saline-prepared vaginal fluid.   J Low Genit Tract Dis, 15(2): 120-3.

OBJECTIVE.: To determine the interobserver reliability of microscopic assessment of saline-prepared vaginal fluid. MATERIALS AND METHODS.: Blind-paired microscopic assessments of saline-prepared vaginal fluid collected from women presenting for gynecologic care were compared using concordance and weighted chance-corrected agreement statistics (κ). RESULTS.: Vaginal fluid from 105 women was collected and examined by 65 distinct observer pairs. The mean age of participants was 39 years, with ... [Abstract] [Full-text]

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